|
KMID : 1188320150090060805
|
|
Gut and Liver
2015 Volume.9 No. 6 p.805 ~ p.808
|
|
|
Successful Xenograft of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimen from Human Extrahepatic Cholangiocarcinoma into an Immunodeficient Mouse
|
|
Jang Se-Young
Bae Han-Ik
Lee In-Kyu
Park Hwan-Ki
Cho Chang-Min
|
|
|
Abstract
|
|
|
|
Patient-derived tumor xenograft is the transfer of primary human tumors directly into an immunodeficient mouse. Patient-derived tumor xenograft plays an important role in the development and evaluation of new chemotherapeutic agents. We succeeded in generating a patient-derived tumor xenograft of a biliary tumor obtained by endoscopic ultrasound-guided fine-needle aspiration from a patient who had an inoperable extrahepatic cholangiocarcinoma. This patient-derived tumor xenograft will be a promising tool for individualized cancer therapy and can be used in developing new chemotherapeutic agents for the treatment of biliary cancer in the future.
|
|
|
KEYWORD
|
|
|
Cholangiocarcinoma, Endoscopic ultrasound-guided fine needle aspiration, Individualized medicine, Xenograft
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|